CompletedNot Applicable

Neuraxial Labor Analgesia and the Incidence of Postpartum Depression

599 participantsStarted 2014-08-01

Plain-language summary

Postpartum depression (PPD) affects approximately 15% of women during the first year after giving birth, and is common across cultures. The etiology of postpartum depression is not totally clear. The severe pain experienced during childbirth was reported to be associated with the development of postpartum depression. The purpose of the present study is to evaluate whether use of neuraxial labor analgesia can reduce the incidence of postpartum depression.

Who can participate

Age range18 Years – 34 Years

SexFEMALE

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Inclusion criteria

✓. Primiparae between 18 and 34 years of age with term single cephalic pregnancy;
✓. Admitted to the delivery room during daytime working hours (from 8 am to 5 pm).
✓. Preparing to deliver vaginally.

Exclusion criteria

✕. History of psychiatric disease (indicate those that are diagnosed before or during pregnancy by psychiatrists);
✕. Presence of contraindications to epidural analgesia, which includes: (1) History of infectious disease of the central nervous system (poliomyelitis, cerebrospinal meningitis, encephalitis, etc.); (2) History of spinal or intra-spinal disease (trauma or surgery of spinal column, intra-spinal canal mass, etc.); (3) Systemic infection (sepsis); (4) Skin or soft tissue infection at the site of epidural puncture; (5) Coagulopathy.
✕. Other reasons that are considered unsuitable for study participation.

What they're measuring

The incidence of postpartum depression

Timeframe: At 42 days after delivery

Trial details

NCT IDNCT02823418

SponsorPeking University First Hospital

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2015-05-29

View on ClinicalTrials.gov More Parturition trials