The primary objective of this observational study is to describe the prevalence of pruritus and pemphigoid in nursing home patients. Secondary outcomes are the relationships of demographic factors and medical risk factors with pemphigoid, including dementia and neuropsychiatric symptoms, medication use and Karnofsky score.
Age range
65 Years
Sex
ALL
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The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
Presence of pruritus
Timeframe: Day 1
Detection of circulating pemphigoid specific IgG autoantibodies by indirect immunofluorescence on 1M salt-split human skin substrate
Timeframe: Day 1
Detection of circulating pemphigoid specific IgG autoantibodies by indirect immunofluorescence microscopy on monkey esophagus substrate
Timeframe: Day 1
Concentration of anti-BP180 NC16A IgG autoantibodies by ELISA
Timeframe: Day 1
Concentration of anti-BP230 IgG autoantibodies by ELISA
Timeframe: Day 1
Detection of circulating pemphigoid specific IgG autoantibodies by immunoblot of keratinocyte extract
Timeframe: Day 1