CompletedNot Applicable

Protein Supplementation and Skeletal Muscle Healing Process

Greece14 participantsStarted 2014-05

Plain-language summary

In this study the investigators utilized protein supplementation over an 8-day period following eccentric exercise-induced muscle damage in order to test the initial hypotheses : i) protein supplementation after exercise-induced muscle injury affects exercise-induced aseptic inflammation and muscle performance.

Who can participate

Age range18 Years – 30 Years

SexMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * a) recreationally trained as indicated by the maximal oxygen consumption levels (VO2max \> 45 ml/kg/min), b) engaged in systematic exercise at least three times per week for \> 12 months, c) non-smokers, d) abstained from any vigorous physical activity during the study, e) abstained from consumption of caffeine, alcohol, performance-enhancing or antioxidant supplements, and medications during the study. Exclusion Criteria: * a) a recent febrile illness, b) history of muscle lesion, c) lower limb trauma

What they're measuring

Change in reduced glutathione in blood

Timeframe: 1h before exercise, 2h post-exercise, daily for 8 days post-exercise

Change in protein carbonyls in serum

Timeframe: 1h before exercise, 2h post-exercise, daily for 8 days post-exercise

Change in protein carbonyls in muscle

Timeframe: 1h before exercise, 2 days post-exercise, 8 days post-exercise

Change in thiobarbituric acid and reactive substances in serum

Timeframe: 1h before exercise, 2h post-exercise, daily for 8 days post-exercise

Change in oxidized glutathione in blood

Timeframe: 1h before exercise, 2h post-exercise, daily for 8 days post-exercise

Change in total antioxidant capacity in serum

Timeframe: 1h before exercise, 2h post-exercise, daily for 8 days post-exercise

Change in catalase activity in serum

Timeframe: 1h before exercise, 2h post-exercise, daily for 8 days post-exercise

Trial details

NCT IDNCT02816411

SponsorUniversity of Thessaly

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2016-02

View on ClinicalTrials.gov More Skeletal Muscle Damage trials

Plain-language summary

Who can participate

Age range18 Years – 30 Years

SexMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

Change in reduced glutathione in blood

Timeframe: 1h before exercise, 2h post-exercise, daily for 8 days post-exercise

Change in protein carbonyls in serum

Timeframe: 1h before exercise, 2h post-exercise, daily for 8 days post-exercise

Change in protein carbonyls in muscle

Timeframe: 1h before exercise, 2 days post-exercise, 8 days post-exercise

Change in thiobarbituric acid and reactive substances in serum

Timeframe: 1h before exercise, 2h post-exercise, daily for 8 days post-exercise

Change in oxidized glutathione in blood

Timeframe: 1h before exercise, 2h post-exercise, daily for 8 days post-exercise

Change in total antioxidant capacity in serum

Timeframe: 1h before exercise, 2h post-exercise, daily for 8 days post-exercise

Change in catalase activity in serum

Timeframe: 1h before exercise, 2h post-exercise, daily for 8 days post-exercise