TerminatedNot Applicable

Dynamic Evaluation of Ankle Joint and Muscle Mechanics in Children With Spastic Equinus Deformity Due to Cerebral Palsy

Stopped: lack of inclusion

France24 participantsStarted 2016-09-08

Plain-language summary

This research will lead to the first evaluation of intrinsic and dynamic joint and muscle mechanics of equinus in cerebral palsy. It would provide a direct cause and effect relationship between equinus and bone deformity. Mechanical insights to the pathophysiology of the targeted muscles will lead to better understanding and, thus, to a better medical and surgical management of equinus deformity. Secondary aim will provide an important insight whether key gait parameters can be exclusively relied upon for surgical treatment planning and evaluation. In a medium-term perspective, depending upon the results of this study, dynamic MRI of the ankle joint may serve as a guiding tool for fixed equinus surgery in case of cerebral palsy.

Who can participate

Age range7 Years – 14 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Equinus cohort inclusion criteria: * children between 7 and 14 years old * with unilateral CP and GMFCS score of I or II * with the presence of fixed equinus defined as a fixed limitation of dorsiflexion inferior to 0° Control cohort inclusion criteria: * age and gender matched to equinus cohort * no history of lower limb musculo-skeletal injury in past 6 months * no history of lower limb musculoskeletal surgery in past six months * no contraindications to MRI Equinus cohort exclusion criteria: * history of lower limb musculo-skeletal surgery * botulinum toxin injection in past 6 months * contraindications to MRI * Uncooperative patient who refused to sign the informed consent * Patient unable to understand the protocol, under guardianship * Patients not affiliated to the Social Security. Control cohort exclusion criteria: * Uncooperative patient who refused to sign the informed consent * Patient unable to understand the protocol, under guardianship * Patients not affiliated to the Social Security.

What they're measuring

Talocrural joint flexion, pronation, and internal rotations

Timeframe: One year

Subtalar joint flexion, pronation, and internal rotations

Timeframe: one year

Achilles tendon moment arm (MAAT)

Timeframe: one year

Trial details

NCT IDNCT02814786

SponsorUniversity Hospital, Brest

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2019-04-18