CompletedNot Applicable

Monitoring of Cerebral Oxygenation Using Jugular Oximetry in Comatose Patients After Cardiac Arrest

Czechia40 participantsStarted 2016-06

Plain-language summary

The use of protective ventilation (to maintain normoxia and normocapnia), optimise haemodynamics, diagnose/treat seizures, therapeutic hypotermia etc is recommended for ICU management of patients who have had cardiac arrest and remain in coma after return of spontaneous circulation according to the latest International Guidelines. These actions essentially aim to limit secondary brain injury but despite all therapeutic effort, the cerebral oxygenation may remain inadequate and there is no validated method to avoid such a state in real time.

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * age 18 or older * successful cardiopulmonary resuscitation * persistent coma defined as: no eye opening to voice and inability to follow commands Exclusion Criteria: * pre-existing "do not resuscitate" status * severe coexisting systemic disease with a limited life expectancy * pregnancy * patients who will die within 72 h of the initial cardiac arrest

What they're measuring

Oxygen Saturation of Jugular Venous Bulb

Timeframe: 24 months

Serum S100B level

Timeframe: 24 months

Serum NSE level

Timeframe: 24 months

BIS monitor guided sedation to level 40-60

Timeframe: 24 months

Trial details

NCT IDNCT02806778

SponsorUniversity Hospital Ostrava

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2018-06

View on ClinicalTrials.gov More Cerebral Hypoxic Injury trials