CompletedNot Applicable

Treatment Outcomes of ReACT for PNES

United States94 participantsStarted 2016-06

Plain-language summary

This research study is examining the effects of Retraining and Control Therapy (ReACT; an intervention focused on changing behaviors and thoughts) for psychogenic non-epileptic seizures (PNES, episodes resembling epileptic seizures but with no medical explanation). Participants engage in 8 individual therapy sessions consisting of either cognitive behavioral therapy or supportive therapy. Healthy control participants also complete pre-questionnaires and two computer tasks.

Who can participate

Age range9 Years – 18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * 9-18 years old. * Diagnosis of psychogenic non-epileptic seizures by a medical doctor using video/EEG. * Family member (parent if a minor) willing to participate and that the subject with PNES chooses. Exclusion Criteria: * Substance use. * Psychosis. * Severe intellectual disability * Diagnosis of epilepsy is acceptable as long as patient's neurologist confirms that epileptic seizures are currently under control. Healthy controls are matched on age (+ or - 1 year), sex, race and family income and can have no psychiatric or medical diagnosis.

What they're measuring

PNES Frequency

Timeframe: 14 months (4 months from baseline to 2 months after the final therapy session and then again for 30 days at the 1-year followup)

Stroop Task

Timeframe: 4 months

Magic and turbulence task

Timeframe: 4 months

Trial details

NCT IDNCT02801136

SponsorUniversity of Alabama at Birmingham

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2021-12

View on ClinicalTrials.gov More Convulsion, Non-Epileptic trials