CompletedNot Applicable

Metabolism Characteristics in the Children With Narcolepsy

France24 participantsStarted 2013-12-20

Plain-language summary

A significant weight gain and obesity are observed for most patients with narcolepsy, mainly at the beginning of the disease and narcolepsy in young children. There is no specific study on the population and the consequences of overweight in the lives of these long-term patients. Narcoleptic patients gain weight significantly at the onset of their illness. It is also known that weight gain is not related to the treatment of narcolepsy. The etiology of obesity in narcoleptic patients is not established. Several assumptions were made (physical activity, leptin diet, metabolism). The reason and the pathophysiology of overweight and obesity in this population therefore remain unclear. In this study, potential change in the total metabolism (24h) for narcoleptic children that could explain their tendency to obesity will be assessed ?

Who can participate

Age range6 Years – 18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: NARCOLEPTIC PATIENTS * Girl or boy age\> 6 years \<18 years; * Narcoleptic: defined by the ICSD diagnostic criteria 2 (International Classification of Sleep Disorders) * Beginning of the troubles there more than 6 months * Parental consent and agreement of the child. HYPERSOMNIC PATIENTS * Girl or boy age\> 6 years \<18 years; * Hypersomnic : defined by the ICSD diagnostic criteria 2 (International Classification of Sleep Disorders) * Beginning of the troubles there more than 6 months * Parental consent and agreement of the child. Exclusion Criteria: NARCOLEPTIC PATIENTS * Secondary Narcolepsy; * Narcolepsy already treated with psychostimulant or anticataplectic; * Restless legs; * Sleep apnea syndrome; * Obesity known outside narcolepsy cause; * Absence of parental consent. HYPERSOMNIC PATIENTS * symptomatic or secondary hypersomnia; * Hypersomnia already treated psychostimulant or anticataplectic; Restless legs; * Sleep apnea syndrome; * Pathology neurological, psychiatric, endocrine or concurrent; * Lack of parental consent

What they're measuring

Determination of the metabolism at home

Timeframe: 15 days

Trial details

NCT IDNCT02799849

SponsorHospices Civils de Lyon

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2018-09