TerminatedNot Applicable

Preoperative IMRT for Soft Tissue Sarcoma of the Extremities and Trunk: Low Rate of Wound Complications

Stopped: Principal Investigator has left the Institution

Switzerland67 participantsStarted 2016-01

Plain-language summary

Postoperative wound healing complications following preoperative radiotherapy represent a severe problem in the treatment of malignant soft tissue tumors, and are reported to be 34% and more. The literature discusses intensely the advantages and disadvantages of this multimodal treatment concept and there are different opinions. The Canadian prospective randomized NCIC SR2 trial showed increased wound complication rates in the study arm receiving preoperative radiation. The Sarcoma Center Zurich pursues mainly this treatment concept and the results shall now be analysed and published. The approach is to show that not only the complication rates are comparable to international bench marks, but also the (still intermediate time) local control rates.

Who can participate

Age range18 Years – 110 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients with a malignant soft tissue tumour * Patients who underwent preoperative radiotherapy at the department of radiation oncology, University Hospital Zurich (USZ) * Surgical treatment at Balgrist University Hospital between 2007 and 2016 Exclusion Criteria: * Vulnerability * Previous chemotherapy * Previous radiotherapy on the affected site * Patient's wish

What they're measuring

Major and minor wound healing complications

Timeframe: through study completion, minimum 6 weeks post surgery

Trial details

NCT IDNCT02785692

SponsorBalgrist University Hospital

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2018-07

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