Differentiated Care for Improved Health Systems Efficiency and Health Outcomes in Zambia (NCT02776254) | Clinical Trial Compass
CompletedNot Applicable
Differentiated Care for Improved Health Systems Efficiency and Health Outcomes in Zambia
Zambia3,100 participantsStarted 2016-03
Plain-language summary
This study seeks to create generalizable knowledge about the implementation process as well as the effectiveness and efficiency of a differentiated care system, by measuring patient health outcomes and implementation outcomes such as acceptability, feasibility, fidelity, and costs
Who can participate
Age range
15 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* HIV-positive adolescents and adults (\> 14 years of age)
* Last CD4 count (obtained within the last six months) \> 200
* Not acutely ill
* For CAGs, UAGs, and Fast-Track models: on ART for at least 6 months
* For the START model: ART naïve and meet the Zambian HIV guidelines for treatment initiation
Exclusion Criteria:
* For CAGs, UAGs: Inability to participate in the group activities due to cognition deficits or mental illness.
* Unable to provide consent or unwilling to participate in study
* Pregnancy
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Retention in care (Time to first missed pharmacy pick-up)
Timeframe: 12 months
Trial details
NCT IDNCT02776254
SponsorCentre for Infectious Disease Research in Zambia