CompletedNot Applicable

Association Between Telomere Length and Risk of Acute Coronary Syndrome

China400 participantsStarted 2016-01

Plain-language summary

Compelling epidemiological evidence indicates that alterations length of telomere, are associated with the initiation and development of ischemic heart disease. This study was undertaken to investigate whether mtDNA copy number in peripheral blood leukocyte could be used as a risk predictor for acute coronary syndrome.

Who can participate

Age range18 Years – 85 Years

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Inclusion criteria

✓1.History of documented myocardial infarction; 2.Prior coronary revascularization intervention (coronary artery bypass graft surgery or percutaneous coronary intervention); 3.The presence of≥50% stenosis in one or more coronary arteries identified during cardiac catheterization;

Exclusion criteria

✕1.History of malignancy or end-stage renal disease; 2.Blood transfusion within one month or prior bone marrow transplantation 3.Patients who reluctant to sign informed consent

What they're measuring

Relative telomere length

Timeframe: From date of percutaneous coronary intervention until the date of discharging from hospital, assessed up to 5 days

Trial details

NCT IDNCT02775279

SponsorAir Force Military Medical University, China

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2016-05

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