CompletedNot Applicable

Thiamine Supplement in Patients With Severe Hyperthyroidism

Thailand12 participantsStarted 2014-01

Plain-language summary

Thyrotoxicosis is a hypermetabolic state in which there is increased utilization of thiamine. Thiamine deficiency has been observed in association with hyperthyroidism. Several studies documented that thiamine treatment could improve signs and symptoms of congestive heart failure, or even improve left ventricular ejection fraction in patients without thyrotoxicosis. This pilot study aims to evaluate prevalence of thiamine deficiency and assess improvement of cardiovascular function after receiving thiamine supplement in thyrotoxic patients.

Who can participate

Age range15 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Hospitalized patients with severe thyrotoxicosis * Thyrotoxic patients with cardiovascular involvement e.g. heart rate \> 90/min, atrial fibrillation or congestive heart failure * Agree to participate by written informed consent Exclusion Criteria: * Previously treated with thiamine within 1 month before the enrollment * End-stage renal disease * Alcoholism * Pregnant or lactating women * Post gastric bypass surgery

What they're measuring

left ventricular systolic function

Timeframe: 3 months

Trial details

NCT IDNCT02767245

SponsorRamathibodi Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2016-07

View on ClinicalTrials.gov More Thyrotoxicosis trials