CompletedNot Applicable

Symptomatic Treatment of Excessive Dynamic Airway Collapse Using Daytime Portable Continuous Positive Airway Pressure

United Kingdom21 participantsStarted 2016-09

Plain-language summary

The aim of this study is to assess the benefit of a portable ventilator generating positive end-expiratory pressure on exercise tolerance in patients with Excessive dynamic airway collapse (EDAC) and tracheobronchomalacia (TBM).

Who can participate

Age range18 Years – 80 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patient with diagnosed EDAC or TBM on inspiratory/expiratory CT or bronchoscopy * Patient with exertional dyspnea Exclusion Criteria: * Pregnancy * Significant physical or psychiatric comorbidity that would prevent compliance with trial protocol * Inability to perform 6-MWT * Current intra-tracheal stent * Previous surgery for EDAC or TBM * Uncontrolled underlying disease: * Initiation of home mechanical ventilation in last 3 months * Uncontrolled joint pain

What they're measuring

Does daytime activity by an accelerometer change from baseline to 4 weeks

Timeframe: 4 weeks

Trial details

NCT IDNCT02763631

SponsorGuy's and St Thomas' NHS Foundation Trust

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2017-06-14

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