CompletedNot Applicable

Cognitive Recovery After Electroconvulsive Therapy and General Anesthesia

United States17 participantsStarted 2016-04

Plain-language summary

This study is geared toward characterizing the recovery of brain activity and cognitive function following treatments of electroconvulsive therapy and ketamine general anesthesia.

Who can participate

Age range18 Years – 60 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Treatment resistant depression requiring outpatient ECT * Planned right unilateral ECT stimulation * English speaking * Able to provide written informed consent Exclusion Criteria: * Known brain lesion or neurological illness that causes cognitive impairment * Schizophrenia * Schizoaffective disorder * Blindness or deafness or motor impediments that may impair performance for cognitive testing battery * Inadequate ECT seizure duration with etomidate

What they're measuring

Change in Cognitive Function During Recovery: Rate of Recovery

Timeframe: 0, 30, 60, 90, 120 minutes following return of consciousness, assessed on treatment days 1-6.

Change in Cognitive Function During Recovery: Initial Decrement

Timeframe: 0, 30, 60, 90, 120 minutes following return of consciousness, assessed on treatment days 1-6.

Trial details

NCT IDNCT02761330

SponsorWashington University School of Medicine

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2019-09-11

Results submitted2020-09-11

View on ClinicalTrials.gov More Depression trials