CompletedNot Applicable

The Right Ventricular Responses to Mild Hypercarbia After Mitral Valve Repair Surgery

Finland31 participantsStarted 2016-04

Plain-language summary

The aims of the study is to investigate the right ventricular responses to mild hypercarbia after mitral valve prolapse repair surgery by the measurements obtained on pulmonary arterial catheter and transesophageal echocardiography.

Who can participate

Age range18 Years – 80 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * scheduled mitral valve prolapse repair surgery * able to give informed consent Exclusion Criteria: * preoperative right ventricular dysfunction or pulmonary hypertension * significant tricuspid regurgitation * congenital heart defect * ventricular dyssynchrony or wide QRS-complex on ECG (\> 130 ms) * prior myocardial infarction (within tree months) or pericardial constriction * preoperative left ventricular (LV) dysfunction, i.e. LV ejection fraction under 40 % * if the scheduled repair by plastic procedure has been converted to mitral valve replacement

What they're measuring

Tricuspid annular plane systolic excursion (TAPSE)

Timeframe: Change from baseline TAPSE at hypercarbia (in approximately 30 min)

Mean pulmonary artery pressure (MPAP)

Timeframe: Change from baseline MPAP at hypercarbia (in approximately 30 min)

Trial details

NCT IDNCT02757573

SponsorTampere University Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2018-12

View on ClinicalTrials.gov More Heart; Decompensation, Right Ventricle trials