Evaluating the Neurobiological Basis of Traumatic Dissociation in Women With Histories of Abuse a… (NCT02757339) | Clinical Trial Compass
By InvitationNot Applicable
Evaluating the Neurobiological Basis of Traumatic Dissociation in Women With Histories of Abuse and Neglect
United States200 participantsStarted 2015-06
Plain-language summary
This study aims to evaluate the neurobiological basis of traumatic dissociation in a cross-diagnostic sample of women who have histories of childhood abuse and neglect.
Who can participate
Age range
18 Years – 89 Years
Sex
FEMALE
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Female
* Clinical diagnosis of PTSD or DID and history of childhood abuse, or healthy controls
* Age between 18 and 89
* Legal and mental competency of the patient
Exclusion Criteria:
* Male
* Under 18 or over 89
* Legal or mental incompetence
* Delirium secondary to medical illness
* PTSD or DID due to general medical or neurological illness
* History of neurological conditions that may cause significant psychiatric symptomatology (e.g., dementia)
* Any contraindication to MR scans, including claustrophobia, pregnancy, metal implants, etc.
* Current alcohol or substance dependence or abuse (within the last month)
* A history of schizophrenia or other psychotic disorder
* History of head injury or loss of consciousness for longer than 5 min (including concussion)
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Change from Baseline correlates of traumatic dissociation in Functional Magnetic Resonance Imaging at 36 to 56 weeks
Timeframe: Baseline and 36 to 56 weeks after baseline