CompletedNot Applicable

The Effect of Anesthetics Agents on Vascular Injury and Level of Syndecan-1 During Knee Surgery

South Korea80 participantsStarted 2016-05-30

Plain-language summary

Ischeic reperfusion injury lead to a cellular dyfunction and increase in soluble glycocalyx of blood flow. syndecan-1 was a marker of glycocalyx. The purpose of this study is to prove the variation of level of serum syndecan-1 between preoperative and postoperative period.

Who can participate

Age range20 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * patients who was planned to undergo knee surgery. Exclusion Criteria: * age \< 20 years old * history of previous cancer * history of previous peripheral vascular disease * Emergency surgery

What they're measuring

Syndecan-1

Timeframe: Preoperative time, Immediate before tourniquet off,5 min after tourniquet off,PACU, postoperation after 6hours, postoperation after 24hours

Trial details

NCT IDNCT02756715

SponsorKonkuk University Medical Center

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2018-03-26

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