CompletedPhase 3

Bone Regeneration With Mesenchymal Stem Cells

20 participantsStarted 2010-04

Plain-language summary

Mandible fractures are a common cause of facial injury in adults. The autologous mesenchymal stem cell (AMSC) transplantation, is proposed as an alternative to the conventional graft treatment, improving bone neoformation.The objective was to evaluate the effectiveness of AMSCs application in mandibular fractures to reduce regeneration time and increase bone quality.

Who can participate

Age range17 Years – 59 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Entitled patients to the Mexican Institute of Social Security * Patients with mandibular condyle fractures associated or not to other initial fracture that required Open reduction and internal fixation * Ages from 17 to 59 years * Both female and male gender * Patients who gave their consent to be part of this trial Exclusion Criteria: * Patients younger than 17 years and older than 59 years * Chronic-degenerative diseases, active smoking, collagen disorders * Patients with signs of infection in the aimed area to treat and in whom the fracture occurred in a longer period than 10 days before their surgery.

What they're measuring

Change of bone quality

Timeframe: from the moment of fracture diagnosis to week 4 and week 12 after surgery

Change of bone quality

Timeframe: from the moment of fracture diagnosis to week 4 and week 12 after surgery

Trial details

NCT IDNCT02755922

SponsorInstituto Mexicano del Seguro Social

Sponsor typeOTHER_GOV

Study typeINTERVENTIONAL

Primary completion2010-09

View on ClinicalTrials.gov More Mandibular Fractures trials