An Investigation Into the Role of Walking in Treating the Symptoms of Knee Osteoarthritis: The Wa… (NCT02748291) | Clinical Trial Compass
CompletedNot Applicable
An Investigation Into the Role of Walking in Treating the Symptoms of Knee Osteoarthritis: The WalkOut Study
United Kingdom9 participantsStarted 2015-01
Plain-language summary
There are over 8.75 million people in the United Kingdom with osteoarthritis in their knees. The effect of this condition can be debilitating. Symptoms are due to wear and tear of the knee joint. Some people can suffer with knee pain and stiffness. This study will look at whether walking improves the symptoms of knee osteoarthritis.
Investigators will recruit anyone with knee pain over the age of 45 years in Nottingham. Participants will undergo a full assessment by a qualified Doctor. After assessment, Participants meeting the eligibility criteria will be invited to join the study. Participants will be randomly allocated into 2 groups. One group will receive standard health and exercise advice. The other group will be allocated a walking activity. This group will undertake 6,000 walking steps each day. Participants will provide pedometers to monitor this walking activity.
The effect of walking will be compared using questionnaires. These will look at pain levels, quality of life and physical activity. The participants will complete these questionnaires before the study, at the 6 week midpoint and at the end of the 12 week intervention.
Who can participate
Age range
45 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
Following current NICE (The National Institute for Health Care Excellence) guidelines (United Kingdom) for diagnosing knee osteoarthritis:
* Anyone over the age of 45 with painful knee/s
* No morning stiffness or stiffness that lasts less than 30 minutes
Exclusion Criteria:
* Exercise/activity \> than current Department of Health physical activity guidelines
* Stiffness \> 30mins in the morning
* Self-reported knee pathology (cruciate, meniscal, soft tissue, joint replacement)
* Cardiac disease - any:
* Acute coronary syndrome \< 12 months
* Unexplained arrhythmia
* Angioplasty/cardiac surgery
* Congestive Cardiac Failure
* Valvular disease
* Cardiomyopathy
* Myocarditis
* Uncontrolled Hypertension
* Thrombolic events - any:
* Cerebrovascular accident/transient ischaemic attack last 12 months
* Deep vein thrombosis/pulmonary embolus last 6 months
* Asthma/Chronic Obstructive Pulmonary Disease Peak Expiratory Flow Rate \< 300L/min/frequent exacerbations
* Anaemia Haemoglobin \<90d/L
* Mental illness/learning disabilities/terminal illness
* Does not understand English
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Objective assessment of participant aerobic capacity and physical function measured in the 6 Minute Walk Test