CompletedNot Applicable

Type 2 Diabetes Affect Exercise Induced Improvement in Insulin Sensitivity

United States50 participantsStarted 2016-04

Plain-language summary

This study investigates whether: (i) a family history of type 2 diabetes affects exercise induced improvements in insulin sensitivity. (ii) being prediabetic affects exercise induced improvements in glycemic control. (iii) sex differences affect exercise induced improvements in glycemic control.

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Sedentary/moderately active lifestyle * Less than 150 minutes/wk. of structured exercise * Physical activity level ≤ 1.4 Exclusion Criteria: * Evidence of significant cardiovascular disease * Screening blood pressure \>140/90 * Pregnancy or breastfeeding * Use of drugs affecting energy metabolism or body weight * Excess alcohol, drug abuse, and smoking * Eating disorder or eating attitudes interfering with study * Excessively or active individuals * Unwillingness to abide by randomization * Injury that prevents the performance of exercise

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Insulin sensitivity

Timeframe: 8-weeks

Glycemic control (long term)

Timeframe: 8-weeks

Glycemic control (postprandial)

Timeframe: 8-weeks

Glycemic variability

Timeframe: 8-weeks

Trial details

NCT IDNCT02745613

SponsorUniversity of Texas, El Paso

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-05

View on ClinicalTrials.gov More Insulin Sensitivity/Resistance trials

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.