CompletedPhase 3

To Evaluate the Efficacy of Supplementation With L. Reuteri + Vit. D3 in Asthmatic Children

Italy52 participantsStarted 2014-04

Plain-language summary

The purpose of this project is to evaluate in a randomized clinical trial, double-blind, controlled, the effects of a dietary supplement containing Lactobacillus reuteri DSM 17938 and vitamin D3 in reducing bronchial inflammation and improve asthma control in patients in children with mild / moderate persistent asthma .

Who can participate

Age range6 Years – 14 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients aged between 6 and 14 years old, of both sexes * Diagnosis of mild / moderate persistent asthma (GINA step 2/3) * Allergy mite (Dermatophagoides farinae and pteronyssinus + + + / + + + +) * Levels of vitamin 25 (OH) D \<30 ng / ml * Signature of the informed consent of one parent or a legal representative Exclusion Criteria: * Cardiovascular disease or systemic * anatomical abnormalities * Other respiratory diseases * Taking probiotics and / or prebiotics in the previous 2 weeks * Taking vitamin D or systemic corticosteroids within 4 weeks * Participation in other clinical trials

What they're measuring

Reduction of allergic bronchial inflammation

Timeframe: Up to 3 months

Reduction of allergic bronchial inflammation

Timeframe: Up to 3 months

Trial details

NCT IDNCT02734446

SponsorUniversity of Campania Luigi Vanvitelli

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2015-02

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