Persistence of Zika Virus in Semen After Acute Infection

Inclusion Criteria: * Male sex * Age 18 years or older * Confirmed ZIKV case, defined as: * Having traveled to an affected area and developing at least 2 of the following Zika virus disease compatible symptoms within 2 weeks of travel: fever defined as T≥ 37.8°C (axillary measurement), maculopapular rash, arthralgia or non-purulent conjunctivitis. * Zika virus diagnosis by:RNA detection by RT-PCR in serum or urine during the first 10 days after infection, OR Four-fold or greater change in virus-specific quantitative antibody titers in paired sera, OR Virus-specific Immunoglobulin M (IgM) antibodies in serum with confirmatory virus-specific neutralizing antibodies in the same or a later specimen Exclusion Criteria: * History of, or ongoing urologic malignancy or urologic surgical treatment (including vasectomy). * Recent (\< 2 years) history of, or ongoing urinary tract infection (including prostatitis, epididymitis, sexually transmitted diseases).