UnknownPhase 2

Photodynamic Therapy in Locally Advanced Hilar Cholangiocarcinoma

South Korea32 participantsStarted 2016-01

Plain-language summary

To determine the safety and efficacy of photodynamic therapy with a novel photosensitizer and a flexible laser probe in locally advanced hilar cholangiocarcinoma.

Who can participate

Age range19 Years

SexALL

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Inclusion criteria

✓. Locally advanced cholangiocarcinoma confirmed to be unsuitable for surgical resection
✓. Exhibiting disease progression without distant metastasis after conventional chemoradiation therapy at multidisciplinary team discussion in Asan Medical Center
✓. Pathologically proven cholangiocarcinoma
✓. have a negative pregnancy test if appropriate
✓. ECOG(Eastern Cooperative Oncology Group) Score 0-2
✓. patients to give informed consent and age more than \>19 years

Exclusion criteria

✕. age less than 18 years
✕. previous history of PDT
✕. uncorrectable coagulopathy
✕. refuse to participate
✕. pregnancy
✕. recent participation in another clinical research trial within 30 days
✕. presence of porphyria or hypersensitivity to photosensitizer
✕. Creatinine clearance \< 45ml

What they're measuring

Treatment response using the Response Evaluation Criteria in Solid Tumours (RECIST) criteria

Timeframe: within 1 month

Trial details

NCT IDNCT02725073

SponsorAsan Medical Center

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2017-12

Contact for this trial

Do Hyun Park, MD, PhD

+82-2-3010-32194 dhpark@amc.seoul.kr

View on ClinicalTrials.gov More Treatment Response trials