UnknownNot Applicable

Trial of Monthly Versus Bi-weekly Endoscopic Variceal Ligation for the Prevention of Esophageal Variceal Rebleeding

China60 participantsStarted 2016-03

Plain-language summary

Many physicians suggest repeating EVL every 1-2 weeks until esophageal varices are obliterated to prevent variceal rebleeding， however, the evidences supporting the efficacy of EVL intervals of 1-2 weeks are insufficient.This randomized controlled study was conducted in order to compare the long-term results of EVL when performed at two different results from monthly and bi-weekly treatments.

Who can participate

Age range18 Years – 80 Years

SexALL

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Inclusion criteria

✓. acute or recent bleeding from esophageal varices;
✓. portal hypertension caused by cirrhosis;
✓. age between 18 and 80 yr.

Exclusion criteria

✕. history of endoscopic, pharmacological, interventional or surgical treatment of esophageal varices;
✕. presence of liver failure with a serum total bilirubin concentration greater than 3 mg/dL;
✕. presence of hepatocellular carcinoma or other malignancy;
✕. an association with a cerebral vascular accident, uremia, acute coronary syndrome, or other severe illness;
✕. history of gastric variceal bleeding;
✕. encephalopathy of stage II or worse;
✕. failure to control initial variceal bleeding;
✕. death within 48 h of admission;

What they're measuring

variceal rebleeding rate

Timeframe: 2 years

Trial details

NCT IDNCT02719119

SponsorWest China Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2017-06

Contact for this trial

XUEFENG LUO, MD

+862885422389 luo_xuefeng@yeah.net

View on ClinicalTrials.gov More Esophageal and Gastric Varices trials