CompletedNot Applicable

Maternal and Fetal Compatibility in Assisted Reproductive Technology (ART)-Oocyte Donor Influences Live Birth Rate

Spain200 participantsStarted 2022-01-01

Plain-language summary

Has the maternal KIR haplotype an impact in pregnancy, miscarriage and live birth rates per embryo transfer in donor oocytes -ART by paternal and oocyte donor HLA-C?

Who can participate

Age range18 Years – 45 Years

SexFEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * BMI between 19 - 27 kg/m2 * Blastocyst embryo transfer previous. * Normal karyotype, thrombophylic and immunological results. * Normal clinical history, viral serology, hormonal analysis (TSH, T4, prolactin, estrogen, progesterone), spermiogram, sperm FISH and pelvic ultrasound results. Exclusion Criteria: * Pregnancy women. * Psychiatric disorders. * Uterus alterations. * Polycystic ovary syndrome * Genetic and autoimmune diseases. * Infectious diseases. * Corticoid and immunosuppressant treatments previous.

What they're measuring

Compatibility maternal fetal KIR HLA-C

Timeframe: 2 years

Trial details

NCT IDNCT02718105

SponsorIVI Madrid

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2022-04-01

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