Poly cystic ovary syndrome (PCOS) is the most common endocrine disorder in women of reproductive age, affecting approximately 5%-10% of all females worldwide . PCOS is a hormonal disorder that involves multiple organ systems within the body. Its cardinal features are Hyperandrogenism and polycystic ovary (PCO) morphology. Women with PCOS may complains about irregular menstrual periods or heavy menstrual bleeding, infertility, excessive growth of coarse facial and body hair, obesity, oiliness of the skin, seborrhea, and cystic acne.
Who can participate
Age range18 Years – 45 Years
SexFEMALE
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Premenopausal women between 18-45 years of age and BMI less than 42
* Diagnosed with PCOS by Rottadom Criteria
* Adequate hepatic, renal, Cardiac and hematological functions.
* Patients willing to Participate and give informed consent in writing as well as in audio-visual form for the study.
* Stable weight for last two months (Change of weight\<3kg)
Exclusion Criteria:
* Male
* Post menopausal women
* Women with hysterectomy
* Hyperprolactinemia
* Patients with congenital adrenal hyperplasia
* Patients suffering from Cushing's syndrome
* Acute or chronic Medical illness including Hepatic, Cardiac or renal insufficiency, COPD,Gastrointestinal Disorders
* Uncontrolled Hypertensive or known Diabetics on drugs
* Use of oral contraceptives or HRT for last three months
* Smoking or drug addicts or with psychiatric illness
* Patients diagnosed with androgen secreting tumors.
* Patients with thyroid dysfunction (T3, T4 level is higher than that in normal women of reproductive age)
* Patients with Hypo-gonadotropic and Hypo-gonadism (central origin of ovarian dysfunction)
* Pregnant or lactating mothers
What they're measuring
1
Reduction in Overian volume & Number of overian Cysts