CompletedNot Applicable

Distal Renal Denervation

Russia55 participantsStarted 2013-01

Plain-language summary

Objective of this study is to evaluate whether a distal mode of endovascular renal denervation with the treatment performed primarily in segmental branches of renal artery is more effective than conventional mode of the intervention with the treatment equally distributed within its main trunk for the treatment of drug-resistant hypertension.

Who can participate

Age range18 Years – 80 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * systolic BP is equal or greater than 160 mmHg or diastolic BP is equal or greater than 100 mmHg, * stable (\>3 months) treatment with full doses of at least 3 antihypertensive drugs including a diuretic, * given written informed consent Exclusion Criteria: * secondary hypertension * 24h-mean systolic BP \<135 mmHg, * estimated glomerular filtration rate (eGFR) \< 30 mL/min/1.73 m2, * extended disease of renal artery, * any other clinically important disorders/comorbidities significantly increasing risk of endovascular intervention (investigator's assessment)

What they're measuring

Changes of 24h-mean Systolic BP Assessed by Ambulatory Blood Pressure Monitoring (ABPM)

Timeframe: From baseline to 6 months

Trial details

NCT IDNCT02667912

SponsorTomsk National Research Medical Center of the Russian Academy of Sciences

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2016-07

Results submitted2017-11-20

View on ClinicalTrials.gov More Hypertension, Resistant to Conventional Therapy trials