Preventing Metabolic Side Effects of Thiazide Diuretics With KMgCitrate

Inclusion Criteria: • Treated or untreated stage I hypertension Exclusion Criteria: * Diabetes mellitus, * Renal impairment (serum creatinine \> 1.4 mg/dL), * Any heart diseases such as congestive heart failure, sustained arrhythmia, or coronary heart disease, * Chronic regular NSAID use, * Allergy to thiazide diuretics, * Gastro-esophageal reflux disease (GERD) requiring treatment with acid reducing agents or antacid more than once a week, * Esophageal-gastric ulcer or history of gastrointestinal bleeding, * Chronic diarrhea, vomiting, * Excessive sweating, * Unprovoked hypokalemia (serum K \< 3.5 mmol/L) or hyperkalemia (serum K \> 5.3 mmol/L), * Abnormal liver function test (Aspartate transaminase (AST) or Alanine transaminase (ALT) above upper limit of normal range), * Subjects on any potassium supplement on a regular basis for any reason, such as patients with primary aldosteronism, * Pregnancy, * History of major depression, bipolar disorder, or schizophrenia, * History of substance abuse, * Gout, * Metabolic alkalosis, with serum bicarbonate \> 32 meq/L, * Severe dietary salt restriction, less than1/2 spoonful or 50 meq sodium/day. * Patient with Claustrophobia will not have MRI but can still participate in the study without MRI * Metal implants will not have MRI but can still participate in the study without MRI