Comparison of the Efficacy of Micro-holes vs. Laser-assisted Dermabrasion, for Repigmenting in Vitiligo Skin

Inclusion Criteria: * Men and women aged over 18 years old with a diagnosis of non-segmental lesions that has been stable over three months * The minimum distance between the normal pigmented skin and the test area should preferably be at least 0.5 cm. * For each patient the lesions are located on the same area (either chest, back, legs or arms) * The lesion area must be: 2cm2 \< lesion\<50cm2 * Treatment resistant areas (failure of at least one medical procedure topical tacrolimus or topical steroids for 6 months). * Absence of infected lesion * Lesions stable for at least one year Exclusion Criteria: * Hypersensibility to local anaesthetics or one of the components of the device (trypsin, hyaluronic acid) * Indication against biopsies * Patient with a history of melanoma * Positive serology (ongoing serious systemic disease, herpes, HIV, hepatitis B and C) * History of keloidal scars and presence of Koebner's phenomenon (type 1 and type 2b) * Infected lesion * Patient with concomitant photosensitizing treatment * Age \<18 years * Major deprived of their freedom by administrative or legal decision, or being the subject of a legal protection measure, or out of state to express their consent * Pregnant,delivering or lactating patients. For the women childbearing potential, a urinary pregnancy test will be done and effective contraception will be expected.