CompletedNot Applicable

Effects of Buprenorphine on Mood in Adults With a Range of Depressive Symptomatology

United States38 participantsStarted 2016-06

Plain-language summary

This study seeks to to study the effects of buprenorphine, a partial mu-opioid agonist, on depressed mood in a healthy young adults with a range of depressive symptomatology.

Who can participate

Age range18 Years – 35 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Healthy adult volunteers * High school education * Fluency in English * BMI between 19 and 30 Exclusion Criteria: * Medical conditions contraindicating study participation * Regularly medication use * Current or past opioid abuse or dependence * Current or past drug or alcohol dependence * Psychiatric illness * Women who are pregnant or nursing

What they're measuring

Subjective Effects as Assessed by Score on "Feel Drug", "Feel High", "Like Drug", and "Want More" Subscales of the Drug Effects Questionnaire Subjective Response With and Without Buprenorphine

Timeframe: 0 through 3 hours after dosing.

Trial details

NCT IDNCT02659787

SponsorUniversity of Chicago

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2017-04

Results submitted2019-04-09

View on ClinicalTrials.gov More Depression trials