Laser Induced Bioengineered Remodeling of Thermally Injured Skin Trial

Inclusion Criteria: * have a burn injury which will be at least 6 months old at the time of first treatment, * have one or more symptomatic burn scars (with at least one or more symptoms such as erythema, pruritus, surface irregularity, or tightness not caused by a contracture that would be better served with surgical treatment), * desire laser treatment, * be at least 6 months of age at the time of treatment, * agree to have no aesthetic treatments for their burn scars, such as peels or fillers, until they have completed the study (two-year period), * agree to be randomized into one of the study's treatment conditions, * agree to return for all treatment and follow-up visits for the two-year study period, * agree to refrain from participating in any other treatment-oriented clinical trial for the duration of this study, and * be able and willing to follow the protocol requirements. Exclusion Criteria: * be women who are pregnant or planning to become pregnant during the study, * have had any previous laser treatment of their burn scars, * have open wounds that are not re-epithelialized in the areas of proposed study treatment, * be taking systemic steroids or immunosuppression medication, * have a connective tissue disorder, * be receiving or planning to receive chemotherapy or radiation during the study, * be medically unable to tolerate anesthesia, or * have other conditions that in the opinion of the investigators or clinicians may affect participant safety or compromi…