UnknownNot Applicable

Cost-effectiveness Evaluation of One Stage Versus Two Stage Exchange for Chronically Infected Total Hip and Total Knee Prostheses

France100 participantsStarted 2018-05-03

Plain-language summary

Chronic infection after total joint arthroplasty generally requires implant exchange. Two stage exchange is considered as the gold standard procedure. However, some authors suggest that one stage exchange may be as effective. No consensus exists in the current literature. The purpose of the study was to evaluate the cost of both strategies in comparison to their success rate.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Age ≥ 18 years * Chronically infected total hip or knee arthroplasty requiring implant exchange * Affiliation to a social security system * Signed informed consent * Effective contraception during all study Exclusion Criteria: * Repeat exchange after failure of a prior treatment for infection * Multiple implant infection * Infection due to mycobacteria or fungus * Pregnancy / Breast feeding * Patient under judicial protection * Impossibility to give informed consent for any reason * Participation to another study

What they're measuring

Cost-utility ratio (ICER)

Timeframe: 12 months post-operative

Trial details

NCT IDNCT02651961

SponsorUniversity Hospital, Strasbourg, France

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2022-10-02

Contact for this trial

Hélène SOAVELO

+33388116559 helene.soavelo@chru-strasbourg.fr

View on ClinicalTrials.gov More Chronically Infected Total Hip of Knee Prosthesis trials