CompletedPhase 1

The Improvement of Limbal Stem Cell Deficiency (LSCD) in Unilateral Stem Cell Damage by Amniotic Membrane Extract Eye Drop (AMEED)

10 participantsStarted 2011-08

Plain-language summary

Corneal epithelial cells and limbal stem cells (LSC) are located in the limbus basal epithelium that are necessary for repair of corneal. About patients with deficient or absence of this area has been proposed various treatments such as limbal stem cell transplantation. This study is a prospective clinical trial to compare the improvement of limbal stem cell deficiency (LSCD) in vivo by using of Amniotic Membrane Extract Eye Drop (AMEED).

Who can participate

Age range18 Years – 50 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patient with unilateral chemical burn (grade III to up); estimation of chemical burns amount and classification was according to Dua. * Without Age limitation Exclusion Criteria: * Lack of timely referral of patients for examinations * Simultaneous use of other drugs that cause impairment of the data

What they're measuring

Limbal defect size

Timeframe: 12 months

Corneal epithelial integrity

Timeframe: 12 months

Corneal epithelial stability

Timeframe: 12 months

Trial details

NCT IDNCT02649621

SponsorRoyan Institute

Sponsor typeOTHER_GOV

Study typeINTERVENTIONAL

Primary completion2012-03

View on ClinicalTrials.gov More Limbal Stem Cell Deficiency (LSCD) trials