CompletedNot Applicable

Incisional Negative Pressure Wound Therapy for Preoperatively Irradiated Lower Extremity Soft Tissue Sarcoma Wounds

United States163 participantsStarted 2015-12

Plain-language summary

This is a study comparing two methods of dressing a post operative wound that are currently in practice. One method is a traditional dry gauze dressing. The other method is using a negative pressure dressing that provides gentle suction on the wound. The investigators will attempt to determine how well the use of post-operative negative pressure dressing reduces wound healing problems in patients who have surgery after radiation for a sarcoma in the thigh or leg.

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Age\>18 * Willing to consent to randomization and able to participate in the study * Lower extremity soft tissue sarcoma necessitating radiation prior to surgical resection * Primary closure of wound * Patients scheduled for surgical resection Exclusion Criteria: * Flap coverage or skin graft * Patients scheduled for amputations as local control of their tumor * Sarcomas where radiation is not planned preoperatively * Repeat surgeries for oncologic reasons (positive margins) * Known allergy to adhesive tape

What they're measuring

Wound Complication Rate

Timeframe: longitudinally up to 6 months postoperatively

Trial details

NCT IDNCT02638298

SponsorMedical University of South Carolina

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-07

Results submitted2025-07-02

View on ClinicalTrials.gov More Sarcoma trials