CompletedNot Applicable

Norwegian Cartilage Project - Microfracture

Norway66 participantsStarted 2016-01

Plain-language summary

114 patients between 18 and 50 years with an isolated focal cartilage defect in the knee will be randomized to either receive arthroscopic microfracture or arthroscopic debridement. Both groups will then undergo a systematic physiotherapy training regime for 6-9 months. The groups will then be compared for results, after 3, 6, 12 and 24 months, by using validated patient reported outcome scores (Lysholm, KOOS, Tegner) and EQ5D as well as clinical examination and radiological findings at 2 years (MRI).

Who can participate

Age range18 Years – 50 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Single symptomatic lesion of the trochlea, medial or lateral femoral condyle of the knee less than 2 cm2 * Cartilage lesion ICRS grade 3 or 4 * More than 50 % of the menisci intact * Ligamentous stable knee * Lysholm Score \< 75 * Acceptable range of motion (5-105 degrees) Exclusion Criteria: * Osteoarthritis * Malalignment \> 5 degrees measured clinically, and if uncertainty on HKA radiographs * Systemic arthritis * Previous cartilage surgery except OCD fixation * Obesity BMI \> 30 * Serious drig or alcohol abuse * Inability to answer questionnaires or partake in rehabilitation * Comorbidity that may influence surgery or rehabilitation * Pregnancy

What they're measuring

Knee Injury and Osteoarthritis Outcome Score (KOOS) Quality of Life

Timeframe: 24 months follow up

Trial details

NCT IDNCT02637505

SponsorUniversity Hospital, Akershus

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-12-31

View on ClinicalTrials.gov More Knee Injury trials