Risk Factors for Variceal Bleeding in Egyptian Patients With Non-Cirrhotic Portal Hypertension (NCT02635815) | Clinical Trial Compass
CompletedNot Applicable
Risk Factors for Variceal Bleeding in Egyptian Patients With Non-Cirrhotic Portal Hypertension
60 participantsStarted 2012-01
Plain-language summary
Background \& Aims: Non-cirrhotic portal hypertension (NCPH) represents a relatively infrequent group of conditions. This work aimed at determining causes of NCPH and evaluating the role of some clinical, laboratory, imaging and endoscopic parameters in prediction of variceal bleeding in an Egyptian cohort with NCPH.
Methods: Sixty patients with non-cirrhotic portal hypertension and oesophageal varices were included. All underwent complete clinical evaluation, laboratory investigations, Color Doppler ultrasonography, platelet count/spleen diameter (mm) ratio and upper gastrointestinal endoscopy. Patients were classified into two groups according to variceal bleeding: (1) Group I: twenty six patients with history of bleeding or had an attack of bleeding during one year follow-up; and (2) Group II: thirty four patients without bleeding.
Who can participate
Sex
ALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Egyptian patients with non-cirrhotic portal hypertension (NCPH) with oesophageal varices
Exclusion Criteria:
* Patients with concomitant infection with viral hepatitis, cirrhotic portal hypertension, hepatocellular carcinoma as well as those with other sources of bleeding such as erosions or ulcers were excluded
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1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
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What they're measuring
1
The presence or absence of variceal bleeding within one year of follow up.