CompletedPhase 4

Effect of Neuromuscular Blockade on Pulmonary Complications in Elective Cardiac Surgery

United States100 participantsStarted 2016-03

Plain-language summary

The investigators will conduct a prospective, randomized trial to assess the impact of neuromuscular blockade on early (\<72 hours post-ICU admission) postoperative respiratory complications in cardiac surgical patients. The study will compare continual neuromuscular blockade with cisatracurium to a single dose of succinylcholine during general anesthesia for cardiac surgery.

Who can participate

Age range18 Years – 90 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Elective cardiac surgery (CABG, valve replacement, CABG + valve) requiring cardiopulmonary bypass Exclusion Criteria: * Emergency surgery * Extremes of age * Previous cardiac surgery * Clinical contraindications to succinylcholine or cisatracurium * Anticipated difficult tracheal intubation * Preoperative mechanical ventilation * Preoperative pharmacologic/mechanical hemodynamic support

What they're measuring

Number of Participants With Postoperative Pulmonary Complications

Timeframe: 72 hours following surgical procedure

Trial details

NCT IDNCT02635542

SponsorUniversity of Chicago

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2017-09-15

Results submitted2018-01-22

View on ClinicalTrials.gov More Neuromuscular Blockade trials