Remote Ischemic Conditioning (RIC) in Recipients of Brain Death Donor Livers - A Feasibility and Safety Study

Inclusion Criteria: * Adults (\> 18 years of age) with acute and chronic liver failure requiring liver transplants or patients undergoing transplantation for hepatocellular carcinoma. * Both sexes * Written consent to participate in the study Exclusion Criteria: * \< 18 years of age * Recipients of split livers * Retransplantation * Recipients of livers combined with other organs * Recipients of livers from cardiac death donors * Lower extremity amputees * History of peripheral vascular disease * Patients taking sulfonylurea anti-diabetic agents at the time of transplant * Patients taking nitrates at the time of transplant * Body mass index \> 45 * Pregnant patients * Patients in whom complete lower extremity ischemia is not achieved despite maximum tourniquet inflation to 250 mmHg during the first intervention * Patients with lower extremity paralysis