This is a pilot study to determine if a standard bolus dose and infusion of dexmedetomidine can significantly decrease the dose of propofol (infusion) required for accomplishing an MRI. The investigators studied three arms to examine the effectiveness of dexmedetomidine. Arm 1 was a single bolus of 1.0 mcg/kg with 1.0 mcg/kg/hr infusion followed by propofol infusion. Arm 2 was a bolus of 1.0 mcg/kg with 0.5 mcg/kg/hr infusion followed by propofol infusion. Arm 3 was only a single bolus of 1.0 mcg/kg with no infusion followed by propofol infusion.
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Dosage/Consumption
Timeframe: Prior to beginning the MRI and throughout the MRI scan - approximately one hour.
Incidence of Patient Movement and MRI Interruption
Timeframe: During the MRI scan, until completion, approximately one hour.
Incidence of Adverse Events
Timeframe: From the time the medication is initiated just (5 minutes) prior to the MRI scan and during the MRI scan and immediately during recovery - approximately one hour and twenty minutes in total.
Case Times
Timeframe: Timeframe immediately before the MRI scan while sedation medication is administered - approximately 10 minutes