Plasticity and Cross-modal Interactions in Profoundly Deaf Adults (NCT02632214) | Clinical Trial Compass
CompletedNot Applicable
Plasticity and Cross-modal Interactions in Profoundly Deaf Adults
France17 participantsStarted 2014-04
Plain-language summary
The aim of this study is to evaluate cerebral asymmetry for face processing in a group of profoundly deaf participants and a group of hearing controls by the mean of fMRI measure. To this end, we present chimeric faces (faces split into different halves), entire faces, or faces presented in divided visual field, and subjects perform a gender categorization task while lying in a fMRI scanner.
It is expected to find a reduced cerebral asymmetry in the Fusiform Face Area in deaf in comparison with hearing participants.
Who can participate
Age range
18 Years – 60 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Consent Form signed
* Medical exam performed before entering in to the scanner
* age between 18 and 60 years
* Absence of neurological and/or psychiatric troubles
* Normal or corrected vision
* Right handed
For Deaf participants:
* Bilateral hearing loss 80 dB or more
* Hearing loss before 2 years of age
* use of French Sign Language
For Hearing participants - signers:
* Absence of hearing loss
* Use of French sign Language (Bilingual)
For Hearing participants - non signers:
* Absence of hearing loss
Exclusion Criteria:
* Pregnant women, mothers who suckle, minors
* Presence of metal implants (cardiac implants, bone implants, auditory implants...),
* Presence of skin implants: not removable body piercings, tattoos, not removable jewels
* Claustrophobia
* Visual impairment without correction
* Neurological/Psychiatric disorder
* Cardiac or respiratory trouble
For Deaf participants:
* unilateral hearing loss
* cochlear implant
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.