CompletedNot Applicable

Plasticity and Cross-modal Interactions in Profoundly Deaf Adults

France17 participantsStarted 2014-04

Plain-language summary

The aim of this study is to evaluate cerebral asymmetry for face processing in a group of profoundly deaf participants and a group of hearing controls by the mean of fMRI measure. To this end, we present chimeric faces (faces split into different halves), entire faces, or faces presented in divided visual field, and subjects perform a gender categorization task while lying in a fMRI scanner. It is expected to find a reduced cerebral asymmetry in the Fusiform Face Area in deaf in comparison with hearing participants.

Who can participate

Age range18 Years – 60 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Consent Form signed * Medical exam performed before entering in to the scanner * age between 18 and 60 years * Absence of neurological and/or psychiatric troubles * Normal or corrected vision * Right handed For Deaf participants: * Bilateral hearing loss 80 dB or more * Hearing loss before 2 years of age * use of French Sign Language For Hearing participants - signers: * Absence of hearing loss * Use of French sign Language (Bilingual) For Hearing participants - non signers: * Absence of hearing loss Exclusion Criteria: * Pregnant women, mothers who suckle, minors * Presence of metal implants (cardiac implants, bone implants, auditory implants...), * Presence of skin implants: not removable body piercings, tattoos, not removable jewels * Claustrophobia * Visual impairment without correction * Neurological/Psychiatric disorder * Cardiac or respiratory trouble For Deaf participants: * unilateral hearing loss * cochlear implant

What they're measuring

cerebral activity (fMRI measure)

Timeframe: Time 0

Trial details

NCT IDNCT02632214

SponsorUniversity Hospital, Grenoble

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2016-12