Persistent Postoperative Pain and Joint Stiffness After Total Knee Arthroplasty Performed for Osteoarthritis

Inclusion Criteria: * Elective primary unilateral total knee arthroplasty * Osteoarthritis with radiologic evidence of "severe narrowing" and/or "bone on bone" in the affected joint * Patients of surgeons who have agreed to participate in the study * Age \> 18 years * American Society of Anesthesiologists (ASA) Physical Status 1-3 * Regional anesthesia * Epidural patient-controlled analgesia (PCA) for postoperative pain * Adductor canal block for postoperative pain Exclusion Criteria: * Contraindication to regional anesthesia, NSAIDs, dexamethasone or acetaminophen * Use of general anesthesia * History of \>6 weeks of daily opioid use and/or any use of non-prescribed opioids * Preoperative oral steroid use in the past 6 months * Intra-articular steroid injection within one month of scheduled surgery in affected joint * Non-English speakers * Pre-existing diagnosis of rheumatic disease or autoimmune disease (e.g. rheumatoid arthritis, psoriatic arthritis, inflammatory bowel disease, multiple sclerosis, Type I diabetes) * Peri-articular injections or infusions for postoperative pain * Diagnosis of crystalline arthropathy * Diagnosis of osteonecrosis * Active infection or use of antibiotics * Pregnant women