CompletedNot Applicable

The Topical Application of Vitamin B6 in Palmar-Plantar Erythrodysesthesia

Cyprus54 participantsStarted 2016-07

Plain-language summary

The study is designed to test the effectiveness of topical B6 cream in patients that developed Palmar-Plantar Erythrodysesthesia (Hand foot syndrome).

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Adult cancer patients (\>18) * Patients receiving capecitabine and/or PLD as monotherapy or in combination with other agents * Patients that will experience PPE grade 1 or above * Willing to participate * Ability to complete the psychometric assessments. * A performance status of two or less on the Eastern Cooperative Oncology Group (ECOG Exclusion Criteria: * Patients with hypersensitivity to Vitamin B. * Patients with pre-existing dermatological condition affecting the hands or/and feet that may limit the interpretation of results * Patients on oral Pyridoxine or nicotine patches * Patients with a previous history of PPE * Patients whose chemotherapy was discontinued for more than a week

What they're measuring

PPE grade

Timeframe: up to 4 weeks

Trial details

NCT IDNCT02625415

SponsorCyprus University of Technology

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2018-05-01

View on ClinicalTrials.gov More Palmar-Plantar Erythrodysesthesia trials