OnabotulinumtoxinA in the Management of Psychogenic Dystonia

Inclusion Criteria: * Subjects must meet standard criteria for clinically definite PsyD;17 * PsyD severity and disability score ≥ 10 as measured by the RSPMD (Appendix 1);10 * Dystonic posturing must have been present without remission for a period longer than 1 year. * Between the ages of 18 and 75, inclusive Exclusion Criteria: * Prior treatment with any BoNT * Presence of clinically unstable medical condition other than the condition under evaluation * Concurrent participation in another investigational drug or device study within 30 days prior to study enrollment. * We will also exclude subjects with medical disorders deemed at increased risk when exposed to BoNT, including myasthenia gravis, Eaton-Lambert syndrome, amyotrophic lateral sclerosis, or other neuromuscular disorders.