Safety and Tolerability of Egalet-002 in Patients With Moderate-to-Severe Chronic Noncancer Pain

Inclusion Criteria: * Is a man or woman between 18 and 75 years of age. * Has a clinical history of moderate-to-severe chronic noncancer pain ≥6 months. * Has required opioid therapy for at least 14 days prior to Screening at a dose between 20 mg and 160 mg (inclusive) oxycodone/day (or opioid equivalent), and will, in the opinion of the investigator, continue to require opioid therapy (between 20 mg and 240 mg oxycodone/day, inclusive) for management of moderate-to-severe pain for the duration of the study. * Has pain either not adequately controlled on current opioid regimen, requires a change of opioid due to tolerability of current opioid regimen or in the opinion of the investigator, would benefit from changing opioid for another reason. * Has stable health, as determined by the investigator. * If female, the patient is currently not pregnant, not breast-feeding, nor attempting to become pregnant (for 30 days before screening through the duration of the study), or is of non-childbearing potential. * Other Criteria Apply Exclusion Criteria: * Has cancer-related pain. * Is receiving \>240 mg oxycodone daily (or opioid equivalent) within 30 days before Screening. * Has a history of attempted suicide. * Has used a spinal infusion pump within 6 months before Screening. * Has clinically unstable cardiac disease (including atrial fibrillation, symptomatic bradycardia, unstable congestive heart failure, or active myocardial ischemia) and/or respiratory disease (including chro…