Impact of Pediatric Acute Renal Injury in Severe Sepsis in Young Adults

Inclusion Criteria: For all patients: • Age 18-24 at time of participation in the study For non-AKI sepsis patients: * Hospitalization with a diagnosis of sepsis from 1998-2014 * Failure to meet pEDRIFLE criteria for AKI during incident sepsis admission * Participation in cognitive survey study with completion of the PedsQL survey For sAKI patients: * Hospitalization with a diagnosis of sepsis from 1998-2014 * Severe AKI as defined by the pEDRIFLE criteria during incident sepsis admission * Participation in cognitive survey study with completion of the PedsQL survey Exclusion Criteria: For all patients: * Known pre-existing CKD as defined by history of kidney transplant or long-term dialysis * Age greater than 18 years at the time of incident sepsis admission * AKI from primary kidney disease including acute glomerulonephritis and obstructive uropathy * Pregnancy at the time of enrollment * Known or suspected allergy to gadolinium based contrast * Known or suspected allergy to iodine or shellfish will be excluded from RPF measurement with iodohippurate * Heart failure or condition whereby the administration of 0.9% normal saline would be contraindicated