CompletedPhase 1

Effect of Broccoli Sprout Extract on Keratinocyte Differentiation in Normal Skin

United States5 participantsStarted 2015-09

Plain-language summary

Adult participants will apply a broccoli sprout extract-jojoba oil compound to one arm every night under occlusion for 1 week. Jojoba oil alone will be applied to the other arm. At the end of 1 week, a 6mm punch biopsy will be taken from both arms and analyzed via polymerase chain reaction (PCR) and immunohistochemistry for differences in various skin proteins.

Who can participate

Age range18 Years

SexALL

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Inclusion Criteria: * Able to attend 3 visits at the designated times. Exclusion Criteria: * Pregnant * Known allergy to broccoli, lidocaine, or epinephrine

What they're measuring

Immunohistochemistry

Timeframe: Within 1 month of skin biopsy

Real time- Polymerase Chain Reaction

Timeframe: Within 1 month of skin biopsy

Trial details

NCT IDNCT02592954

SponsorJohns Hopkins University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2016-12

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