Occurrence of Selected Vitamins in Saliva and Blood (NCT02592148) | Clinical Trial Compass
CompletedNot Applicable
Occurrence of Selected Vitamins in Saliva and Blood
Germany50 participantsStarted 2015-11
Plain-language summary
There is an interest to assess nutritional status of vitamins in humans in a non-invasive way, i.e. by avoiding taking blood samples. Saliva could potentially be an alternative to blood for this purpose. The suitability of saliva for status determination will be investigated by analysis of (forms of) vitamins A and E, B1, B2, B3, B6 and C in both saliva and blood.
Who can participate
Age range20 Years – 65 Years
SexALL
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Inclusion Criteria:
* Generally healthy males and females
* Age: 20-65 years
* Non-smokers
* No recent or recently (within the last four weeks) started intake of vitamin supplements; long-term intake of supplements on regular base is o.k., but needs to be documented (type of supplement and dosage)
* Subjects willing and able to give written informed consent and to understand, to participate and to comply with the biomedical research project requirements.
Exclusion Criteria:
* Any condition that, in the investigator's opinion would impact volunteer safety and/or a volunteer's ability to complete all study related procedures. (e.g. psychiatric illness, drug addiction, alcoholism, etc.)
* Known infection with human immunodeficiency virus (HIV) or hepatitis.
* Chronic intake of substances affecting blood coagulation (e.g. acetylic acid, anticoagulants, diuretics, thiazides), which in the investigator's opinion would impact volunteer safety
* Allergy or known hypersensitivity against disinfection solutions
* Women: pregnancy, or during lactation
* Currently participating in another study
What they're measuring
1
Identify and quantify selected forms of vitamins in saliva and blood/plasma samples