CompletedNot Applicable

Cluster Headache and SPINK-1 Gene

France42 participantsStarted 2011-10

Plain-language summary

Cluster headache (CH) is a rare, excruciating primary headache disorder. A genetic basis has been suggested by family and twin studies, but the mode of transmission seems to vary and the amount of heritability is unclear. The number of genetic association studies investigating variants implicated in the pathophysiology of CH is limited. The HCRTR2 1246G \> A and the ADH4 925A \> G polymorphisms have been associated with CH. The former has been confirmed and may affect the hypothalamic hypocretin system. The aim of the present study was to investigate the possible link between SPINK 1 gene and cluster headache.

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * People aged 18 or over * Patient consulting in Marseille's or Nice's Pain departments * Patient agreeing to participate to the research study * Patient with health insurance Exclusion Criteria: * People aged under 18 * Patient refusing to participate to the research study * Patient with deprivation of liberty

What they're measuring

SPINK1 genotyping

Timeframe: 2 months

Trial details

NCT IDNCT02585739

SponsorAssistance Publique Hopitaux De Marseille

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2013-11

View on ClinicalTrials.gov More Episodic or Chronic Cluster Headache trials