CompletedNot Applicable

Effectiveness of Narrow Margins in Patients With Low-Risk Basal Cell Carcinoma Undergoing Surgery

United States179 participantsStarted 2011-12-07

Plain-language summary

This clinical trial studies the effectiveness of narrow margins in patients with low-risk basal cell carcinoma undergoing surgery to remove skin lesions on the face. A margin is the area of normal tissue around a tumor taken out during surgery to make sure all of the cancer is removed. This clinical trial studies tissue samples to determine the least amount of tissue that must be removed to give an acceptable cure rate. This may allow less normal tissue to be removed from patients and may be a less expensive surgery.

Who can participate

SexALL

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Inclusion criteria

✓. Location
✓. Area M (cheeks, forehead, scalp \& neck) tumor size \< 10 mm
✓. Area H (central face, eyelids, eyebrows, periorbital, nose, lips, chin, mandible, preauricular \& postauricular, temple \& ear) tumor size \< 6 mm
✓. Well-defined borders
✓. Primary BCC
✓. Patient is not immunosuppressed
✓. There has not been prior radiotherapy to the site
✓. Nodular subtype

Exclusion criteria

✕. Location
✕. Area M tumor size \> or = to 10 mm
✕. Area H tumor size \> or = to 6 mm
✕. Poorly defined borders
✕. Recurrent BCC
✕. Patient is immunosuppressed
✕. There has been prior radiotherapy to the site -

What they're measuring

Success rate for 1 mm margins

Timeframe: Up to 3 years

Success rate for 2 mm margins

Timeframe: Up to 3 years

Trial details

NCT IDNCT02579551

SponsorSidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2014-02-01

View on ClinicalTrials.gov More Skin Basal Cell Carcinoma trials