An Observational Study to Investigate the Effects of Rapid Transmeridian Travel

Inclusion Criteria: * Ability and acceptance to provide written consent * Men or women between 18-75 years * Body Mass Index of ≥ 18 and ≤ 30 kg/m2 Exclusion Criteria: * History (within the 12 months prior to screening) of psychiatric disorders * Major surgery, trauma, illness or immobile for 3 or more days within the past month * Pregnancy or recent pregnancy (within 6 weeks) * A positive test for drugs of abuse at the screening visit * Any other sound medical reason as determined by the clinical investigator