CompletedNot Applicable

Does Bowel Stimulation Before Loop Ileostomy Closure Reduce Postoperative Ileus?

Canada101 participantsStarted 2016-12-01

Plain-language summary

Postoperative ileus is the most commonly observed morbidity following ileostomy closure. Studies have previously demonstrated that the defunctionalized bowel of a loop ileostomy undergoes a series of functional and structural changes. It has been hypothesized that these changes may contribute to the development of postoperative ileus, and that stimulating the distal limb of a loop ileostomy prior to closure may functionally prepare the excluded bowel for intestinal transit. The purpose of the multicenter, randomized controlled trial is to determine the impact of preoperative stimulation of the distal limb of a loop ileostomy on postoperative ileus.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * All patients will have undergone an anterior or low-anterior resection for malignant or benign disease with a protective loop ileostomy by a board-certified colorectal surgeon or surgical oncologist at one of the involved sites. Exclusion Criteria: * Patients with a protective ileostomy following colonic resection for Crohn's disease will be excluded from entering the study, as well as patients from whom clear and informed consent cannot be obtained.

What they're measuring

Number of patients with postoperative ileus

Timeframe: Patients will be followed for the duration of hospital stay until discharge, about 30 days

Postoperative length of stay

Timeframe: Patients will be followed for the duration of hospital stay until discharge, about 30 days

Trial details

NCT IDNCT02559635

SponsorJewish General Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2022-01-18

View on ClinicalTrials.gov More Postoperative Ileus trials